Havard Research Group
Prof. Eva Schernhammer has been with the Nurses’ Health Study group since 2000, where her research, relating the influence of night shift work and sleep to chronic diseases and longevity in humans, has been based primarily in the Harvard cohorts, including the Nurses’ Health Studies (NHS) and the Health Professionals Follow-up Study, and a California based cohort study, the Osteoporotic Fractures in Men (MrOS) cohort of older men.
She has longstanding experience with the three NHS cohorts (NHS, NHS2, and NHS3) and continues an active research program at the Channing Division of Network Medicine. In addition to cancer, she examines the effect of circadian misalignment (e.g., variations in circadian and melatonin metabolism genes, melatonin secretion, shift work history, effect modification by chronotype, as well as sleep duration, insomnia, and other sleep parameters) in relation to cardiovascular disease pathways (e.g., markers of inflammation, glucose and lipid metabolism and thrombosis) and associated endpoints. Another research focus has been to study pathways of energy balance including IGFs with respect to breast cancer risk. Further, she is interested in the etiology and prevention of gastrointestinal tumors, including how epigenetic events impact colorectal cancer risk, and how methyl donors interact with these events. In addition, she studies risk factors of Parkinson’s disease and has helped establish the worldwide largest population-based case-control study to examine GxE in PD.
Contact
Channing Division of Network Medicine
181 Longwood Avenue, 3rd Floor
Boston, MA 02115
Phone: (617) 525 - 4648
Fax: (617) 525 - 2008